The news was announced on Tuesday by the White House, and confirmed by Father Federico Lombardi, Head of the Vatican Press Office.
It will be Obama’s first meeting with Pope Francis. At the Inaugural Mass of his Petrine Ministry on March 19, 2013, the United States was represented by US Vice-President, Joe Biden.
The announcement comes just days after the Vatican Secretary of State, Cardinal-designate Pietro Parolin met with US Secretary of State, John Kerry.
During his time in Italy, Barack Obama will also meet with Italian President Giorgio Napolitano, and with Prime Minister Enrico Letta.
In July 2009, Barack Obama was received in audience by Benedict XVI.